Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331264 | 1.00 | ITGA4 (0.40) | ITGA4ITGB7LTB4RMEN1KMT2A | |
| SCHEMBL29423375 | 0.86 | ITGA4 (0.41) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL13331268 | 0.86 | ITGA4 (0.41) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL22690732 | 0.85 | ITGA4 (0.39) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL13331261 | 0.85 | MAPT (0.44) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL29423510 | 0.85 | MAPT (0.44) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL22559414 | 0.84 | KMT2A (0.44) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28693868 | 0.84 | MEN1 (0.37) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL22690734 | 0.84 | ITGA4 (0.42) | ITGA4ITGB7MEN1KMT2ACYP19A1 | |
| SCHEMBL13331267 | 0.82 | ERN1 (0.41) | ITGA4ITGB7MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525928-A1 | ANTIBODY DRUG CONJUGATES | Novartis AG (CH) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023223097-A1 | ANTIBODY DRUG CONJUGATES | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | disclosed |
| EP-3972650-A2 | ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS | Novartis AG (CH) | 2022-03-30 | — | — | EP | disclosed |