Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 17/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 7/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085864 | 0.81 | PIK3CG (0.43) | PIK3CGPIK3CDPIK3R1PIK3R2PIK3CA | |
| SCHEMBL30254739 | 0.80 | ATR (0.34) | PIK3CDATR | |
| SCHEMBL23501318 | 0.77 | NTRK1 (0.42) | — | |
| SCHEMBL23501317 | 0.77 | NTRK1 (0.42) | — | |
| SCHEMBL29424906 | 0.76 | PIK3CG (0.39) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL23501169 | 0.73 | NTRK1 (0.38) | — | |
| SCHEMBL23728636 | 0.72 | PDE2A (0.44) | PIK3CGPDE2A | |
| SCHEMBL26172231 | 0.69 | HTR6 (0.53) | PIK3CGPIK3CDPIK3R2PDE2APIK3CA | |
| SCHEMBL23501000 | 0.68 | IRAK4 (0.41) | PIK3CD | |
| SCHEMBL23501059 | 0.68 | IRAK4 (0.41) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218276-A1 | SOLID FORM OF FLUORINE-CONTAINING MACROCYCLIC STRUCTURE COMPOUND, PREPARATION METHOD, AND APPLICATION | 成都倍特药业股份有限公司 | 2022-10-20 | — | — | WO | disclosed |
| EP-4074715-A1 | FLUORINE-CONTAINING HETEROCYCLIC DERIVATIVES WITH MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2022-10-19 | — | — | EP | disclosed |
| WO-2022033575-A1 | APPLICATION OF FLUORINE-CONTAINING HETEROCYCLIC DERIVATIVE HAVING MACROCYCLIC STRUCTURE | 赛诺哈勃药业（成都）有限公司 | 2022-02-17 | — | — | WO | disclosed |