Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.64 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.63 |
| ▸ | APLNR | P35414 | 5/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.54 |
| ▸ | MC5R | P33032 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
| ▸ | MC1R | Q01726 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839204 | 1.00 | GNRHR (0.64) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL31733948 | 0.97 | GNRHR (0.67) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL29857994 | 0.97 | GNRHR (0.67) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL30198868 | 0.97 | GNRHR (0.66) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL31135225 | 0.96 | C5AR1 (0.64) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL29425250 | 0.96 | GNRHR (0.70) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL30665146 | 0.95 | GNRHR (0.65) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL30773556 | 0.95 | PTGS1 (0.71) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL30839205 | 0.95 | GNRHR (0.64) | GNRHRABCC2PTGS1C5AR1APLNR | |
| SCHEMBL6512254 | 0.95 | PTGS1 (0.71) | GNRHRABCC2PTGS1C5AR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962927-A1 | PEPTIDE DERIVATIVES AND CONJUGATES THEREOF FOR TREATING CANCER | The University of Sydney (AU) | 2022-03-09 | — | — | EP | disclosed |