SCHEMBL29857994

SCHEMBL29857994

CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GNRHR P30968 2/20 0.67
▸ ABCC2 Q92887 1/20 0.67
▸ PTGS1 P23219 1/20 0.66
▸ C5AR1 P21730 2/20 0.59
▸ APLNR P35414 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31733948 1.00 GNRHR (0.67) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL30665146 0.98 GNRHR (0.65) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL29425251 0.97 GNRHR (0.64) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL29858408 0.97 PTGS1 (0.65) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL30839204 0.97 GNRHR (0.64) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL29857989 0.96 GNRHR (0.63) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL30063828 0.95 PTGS1 (0.69) GNRHRABCC2PTGS1C5AR1APLNR
Deslorelin SCHEMBL25353366 0.95 GNRHR (0.74) GNRHRABCC2PTGS1C5AR1APLNR
SCHEMBL31621935 0.95 PTGS1 (0.67) GNRHRABCC2PTGS1C5AR1APLNR
Deslorelin SCHEMBL59413 0.95 GNRHR (0.74) GNRHRABCC2PTGS1C5AR1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 — — US claimed
CN-116199745-A Method for solid-phase synthesis of dilorelin 宁波第二激素厂 2023-06-02 — — CN claimed
US-20230071112-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-03-09 — — US claimed
US-20220313836-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-10-06 — — US claimed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 — — US disclosed
US-12364767-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-07-22 — — US disclosed
US-12285491-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-04-29 — — US disclosed
CN-116199745-A Method for solid-phase synthesis of dilorelin 宁波第二激素厂 2023-06-02 — — CN disclosed
CN-116199745-A Method for solid-phase synthesis of dilorelin 宁波第二激素厂 2023-06-02 — — CN disclosed
US-20230071112-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-03-09 — — US disclosed
US-20220313837-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-10-06 — — US disclosed
US-20220313836-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD4, CD2, B2M GNRHR 3280/4885ABCC2 2214/4885PTGS1 2224/4885
US-20220313836-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM GNRHR 2042/4885ABCC2 1574/4885PTGS1 3643/4885
US-12285491-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM GNRHR 2042/4885ABCC2 1574/4885PTGS1 3643/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 GNRHR 289/4885ABCC2 440/4885PTGS1 3450/4885
US-12364767-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM GNRHR 2042/4885ABCC2 1574/4885PTGS1 3643/4885
US-20220313837-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM GNRHR 2042/4885ABCC2 1574/4885PTGS1 3643/4885
US-20230071112-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM GNRHR 2144/4885ABCC2 1557/4885PTGS1 3659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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