Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.69 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.61 |
| ▸ | GNRHR | P30968 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | NPY4R | P50391 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.56 |
| ▸ | MC5R | P33032 | 1/20 | 0.56 |
| ▸ | MC3R | P41968 | 1/20 | 0.56 |
| ▸ | MC1R | Q01726 | 1/20 | 0.56 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.56 |
| ▸ | NMBR | P28336 | 1/20 | 0.56 |
| ▸ | GRPR | P30550 | 1/20 | 0.56 |
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | GLP1R | P43220 | 2/20 | 0.55 |
| ▸ | GCGR | P47871 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459900 | 0.97 | C5AR1 (0.65) | C5AR1CXCR4GNRHRMC4RNPY1R | |
| Acetic Acid SCHEMBL29810985 | 0.96 | C5AR1 (0.64) | C5AR1CXCR4GNRHRMC4RNPY1R | |
| SCHEMBL29425255 | 0.95 | C5AR1 (0.68) | C5AR1CXCR4MC4RNPY1RNPY2R | |
| SCHEMBL11033870 | 0.94 | C5AR1 (0.65) | C5AR1CXCR4GNRHRMC4RNPY1R | |
| SCHEMBL29942618 | 0.94 | C5AR1 (0.64) | C5AR1CXCR4GNRHRMC4RKISS1R | |
| SCHEMBL30271248 | 0.94 | C5AR1 (0.64) | C5AR1CXCR4GNRHRMC4RKISS1R | |
| Acetic Acid SCHEMBL29811007 | 0.93 | C5AR1 (0.64) | C5AR1CXCR4GNRHRMC4RNPY1R | |
| SCHEMBL29425245 | 0.91 | GNRHR (0.62) | C5AR1CXCR4GNRHRMC4RNPY1R | |
| SCHEMBL29425250 | 0.91 | GNRHR (0.70) | C5AR1CXCR4GNRHRABCC2APLNR | |
| SCHEMBL29750088 | 0.91 | C5AR1 (0.72) | C5AR1CXCR4MC4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211860-A1 | PEPTIDE DERIVATIVES AND CONJUGATES THEREOF FOR TREATING CANCER | THE UNIVERSITY OF SYDNEY (AU) | 2022-07-07 | — | — | US | claimed |
| US-20220211860-A1 | PEPTIDE DERIVATIVES AND CONJUGATES THEREOF FOR TREATING CANCER | THE UNIVERSITY OF SYDNEY (AU) | 2022-07-07 | — | — | US | disclosed |
| EP-3962927-A1 | PEPTIDE DERIVATIVES AND CONJUGATES THEREOF FOR TREATING CANCER | The University of Sydney (AU) | 2022-03-09 | — | — | EP | disclosed |