Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.60 |
| ▸ | MC4R | P32245 | 3/20 | 0.59 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.56 |
| ▸ | MC5R | P33032 | 2/20 | 0.56 |
| ▸ | MC3R | P41968 | 2/20 | 0.56 |
| ▸ | MC1R | Q01726 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | GLP1R | P43220 | 3/20 | 0.54 |
| ▸ | GCGR | P47871 | 3/20 | 0.54 |
| ▸ | NMBR | P28336 | 1/20 | 0.54 |
| ▸ | GRPR | P30550 | 1/20 | 0.54 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425254 | 0.95 | C5AR1 (0.69) | C5AR1CXCR4MC4RKISS1RMC5R | |
| SCHEMBL29391110 | 0.94 | C5AR1 (0.64) | C5AR1CXCR4MC4RKISS1RMC5R | |
| SCHEMBL29459900 | 0.92 | C5AR1 (0.65) | C5AR1CXCR4MC4RKISS1RNPY1R | |
| Acetic Acid SCHEMBL29810985 | 0.92 | C5AR1 (0.64) | C5AR1CXCR4MC4RKISS1RMC5R | |
| SCHEMBL30839204 | 0.90 | GNRHR (0.64) | C5AR1CXCR4MC4RMC5RMC3R | |
| SCHEMBL29425251 | 0.90 | GNRHR (0.64) | C5AR1CXCR4MC4RMC5RMC3R | |
| SCHEMBL29391874 | 0.90 | C5AR1 (0.59) | C5AR1CXCR4MC4RKISS1RMC5R | |
| SCHEMBL11033870 | 0.90 | C5AR1 (0.65) | C5AR1CXCR4MC4RKISS1RMC5R | |
| SCHEMBL31633744 | 0.90 | C5AR1 (0.68) | C5AR1CXCR4MC4RMC5RMC3R | |
| SCHEMBL30181849 | 0.89 | C5AR1 (0.59) | C5AR1CXCR4MC4RKISS1RGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962927-A1 | PEPTIDE DERIVATIVES AND CONJUGATES THEREOF FOR TREATING CANCER | The University of Sydney (AU) | 2022-03-09 | — | — | EP | disclosed |