Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29781364 | 1.00 | MAPK14 (0.34) | MAPK14DHODHCSF1RTGFBR1NUDT1 | |
| SCHEMBL23673897 | 1.00 | MAPK14 (0.34) | MAPK14DHODHCSF1RTGFBR1NUDT1 | |
| SCHEMBL27224638 | 0.89 | DHODH (0.37) | DHODHNUDT1KDM4EMAP2K1 | |
| SCHEMBL23673877 | 0.85 | MAP2K1 (0.37) | MAPK14DHODHCSF1RTGFBR1NUDT1 | |
| SCHEMBL23673984 | 0.84 | KDM4E (0.43) | MAPK14DHODHCSF1RKDM4EMAP2K1 | |
| SCHEMBL29425395 | 0.84 | KDM4E (0.43) | MAPK14DHODHCSF1RKDM4EMAP2K1 | |
| SCHEMBL24848943 | 0.83 | DHODH (0.34) | DHODHCSF1RTGFBR1NUDT1MAPT | |
| SCHEMBL30459905 | 0.82 | MAP2K1 (0.35) | MAPK14DHODHCSF1RTGFBR1NUDT1 | |
| SCHEMBL23673990 | 0.82 | MAP2K1 (0.35) | MAPK14DHODHCSF1RTGFBR1NUDT1 | |
| SCHEMBL23673873 | 0.81 | MAP2K1 (0.35) | MAPK14DHODHCSF1RTGFBR1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803024-A | Composition comprising arylamide derivatives | 中外制药株式会社 | 2023-03-14 | — | — | CN | disclosed |
| CN-114929669-A | Arylamide derivatives having antitumor activity | 中外制药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| WO-2022018875-A1 | ARYLAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CELL PROLIFERATION DISEASES | 中外製薬株式会社 | 2022-01-27 | — | — | WO | disclosed |