Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.35 |
| ▸ | DHODH | Q02127 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673990 | 1.00 | MAP2K1 (0.35) | MAP2K1DHODHMAPK14MAPK13CSF1R | |
| SCHEMBL23673873 | 0.90 | MAP2K1 (0.35) | MAP2K1DHODHMAPK14MAPK13CSF1R | |
| SCHEMBL30866576 | 0.89 | DHODH (0.37) | MAP2K1DHODHMAP2K2KDM4E | |
| SCHEMBL23673877 | 0.85 | MAP2K1 (0.37) | MAP2K1DHODHMAPK14MAPK13CSF1R | |
| SCHEMBL23673984 | 0.84 | KDM4E (0.43) | MAP2K1DHODHMAPK14CSF1RKDM4E | |
| SCHEMBL29425395 | 0.84 | KDM4E (0.43) | MAP2K1DHODHMAPK14CSF1RKDM4E | |
| SCHEMBL24848964 | 0.83 | DHODH (0.36) | MAP2K1DHODHCSF1RTGFBR1MAP2K2 | |
| SCHEMBL29425398 | 0.82 | MAPK14 (0.34) | MAP2K1DHODHMAPK14MAPK13CSF1R | |
| SCHEMBL23673897 | 0.82 | MAPK14 (0.34) | MAP2K1DHODHMAPK14MAPK13CSF1R | |
| SCHEMBL29781364 | 0.82 | MAPK14 (0.34) | MAP2K1DHODHMAPK14MAPK13CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725941-A1 | ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-04-15 | — | — | EP | disclosed |
| EP-4375273-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |
| EP-4186506-A1 | COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-31 | — | — | EP | disclosed |