Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.51 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.51 |
| ▸ | AURKA | O14965 | 4/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.48 |
| ▸ | MAP3K9 | P80192 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | STK3 | Q13188 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693639 | 1.00 | MAP2K1 (0.51) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL23694073 | 0.89 | MAP2K1 (0.50) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL29425421 | 0.89 | MAP2K1 (0.50) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL23693641 | 0.88 | KMT2A (0.61) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL29425373 | 0.88 | MAP2K1 (0.67) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL1562380 | 0.88 | MAP2K1 (0.67) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL24849049 | 0.86 | MAP2K1 (0.56) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL5872850 | 0.86 | MAP2K1 (0.56) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL23673886 | 0.86 | MAP2K1 (0.67) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 | |
| SCHEMBL29425507 | 0.86 | MAP2K1 (0.67) | MAP2K1MAP2K2AURKATNFRSF1AMAP3K9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803024-B | Compositions comprising aryl amide derivatives | 中外制药株式会社 | 2025-01-10 | — | — | CN | disclosed |
| CN-114929669-B | Aryl amide derivatives with antitumor activity | 中外制药株式会社 | 2024-11-29 | — | — | CN | disclosed |
| CN-117677607-A | Process for producing aryl amide derivative | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-115803024-A | Composition comprising arylamide derivatives | 中外制药株式会社 | 2023-03-14 | — | — | CN | disclosed |
| CN-114929669-A | Arylamide derivatives having antitumor activity | 中外制药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| WO-2022018875-A1 | ARYLAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CELL PROLIFERATION DISEASES | 中外製薬株式会社 | 2022-01-27 | — | — | WO | disclosed |