Soman

Soman

SCHEMBL294255

CC(OP(C)(=O)F)C(C)(C)C.CO[PH](=O)F

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Soman SCHEMBL59654 0.86 CTSA (0.40) CTSAACHE
Soman SCHEMBL16218373 0.86 CTSA (0.40) CTSAACHE
Soman SCHEMBL3796733 0.86 CTSA (0.40) CTSAACHE
Soman SCHEMBL30121116 0.84 CTSA (0.39) CTSAACHE
Soman SCHEMBL2592006 0.80 CTSA (0.46) CTSAACHE
Soman SCHEMBL16012017 0.80 CTSA (0.36) CTSAACHE
Soman SCHEMBL7874079 0.80 CTSA (0.36) CTSAACHE
Soman SCHEMBL30565576 0.77 CTSA (0.33) CTSAACHE
Soman SCHEMBL17780216 0.77 CTSA (0.33) CTSAACHE
Soman SCHEMBL28537981 0.74 TDP1 (0.37) CTSAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120100596-A1 DFPASE ENZYMES FROM OCTOPUS VULGARIS NOVOZYMES A/S (DK) 2012-04-26 US disclosed
EP-2427548-A1 DFPASE ENZYMES FROM OCTOPUS VULGARIS Novozymes A/S (DK) 2012-03-14 EP disclosed
EP-2427555-A1 DFPASE ENZYMES FROM APLYSIA CALIFORNICA Novozymes A/S (DK) 2012-03-14 EP disclosed
US-20110039301-A1 Polypeptides Having Organophosphorous Hydrolase Activity and Polynucleotides Encoding Same NOVOZYMES A/S (DK) 2011-02-17 US disclosed
EP-2271753-A1 POLYPEPTIDES HAVING ORGANOPHOSPHOROUS HYDROLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2011-01-12 EP disclosed