⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497821 | 1.00 | — | — | |
| SCHEMBL6940747 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL1834298 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL5683952 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL6937737 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL6936893 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL6940760 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL6940862 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL7569097 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL19850 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060267-A1 | PYRAZOLO COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-03-03 | — | — | US | claimed |
| EP-2970307-A1 | PYRAZOLO COMPOUNDS AND USES THEREOF | Genentech, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| CN-104671676-A | An improved low-refractive index coating for optical fiber, a method for manufacturing the same and a product comprising the same | OFS FITEL LLC | 2015-06-03 | — | — | CN | claimed |
| WO-2014139326-A1 | PYRAZOLO COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| EP-1161222-A1 | METHOD OF TREATING HAIR LOSS USING NON-IMMUNOSUPPRESSIVE COMPOUNDS | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000051558-A1 | METHOD OF TREATING HAIR LOSS USING NON-IMMUNOSUPPRESSIVE COMPOUNDS | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2000-09-08 | — | — | WO | claimed |
| CN-112154167-B | Composition, cured product, optical filter, and method for producing cured product | 株式会社艾迪科 | 2023-08-22 | — | — | CN | disclosed |
| US-20210353555-A1 | NANOPARTICLES BASED ON OPTIONALLY ALKOXYLATED POLY(ALKYL CYANOACRYLATES) HAVING A DEFINED DEGREE OF POLYMERIZATION | AbbVie Deutschland GmbH & Co. KG (DE) | 2021-11-18 | — | — | US | disclosed |
| EP-3377110-B1 | NANOPARTICLES BASED ON OPTIONALLY ALKOXYLATED POLY(ALKYL CYANOACRYLATES) HAVING A DEFINED DEGREE OF POLYMERIZATION | ABBVIE DEUTSCHLAND (DE) | 2021-01-06 | — | — | EP | disclosed |
| EP-2970307-B1 | PYRAZOLO COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-03-11 | — | — | EP | disclosed |
| US-20180325833-A1 | NANOPARTICLES BASED ON OPTIONALLY ALKOXYLATED POLY(ALKYL CYANOACRYLATES) HAVING A DEFINED DEGREE OF POLYMERIZATION | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-11-15 | — | — | US | disclosed |
| EP-3377110-A1 | NANOPARTICLES BASED ON OPTIONALLY ALKOXYLATED POLY(ALKYL CYANOACRYLATES) HAVING A DEFINED DEGREE OF POLYMERIZATION | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-10035801-B2 | Pyrazolo compounds and uses thereof | GENENTECH, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0385692-A2 | Optcally active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0259346-B1 | R-1-CYAN-1-R2 -CIS-4-R1 -CYCLOHEXANE COMPOUNDS | MERCK PATENT GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4818429-A | FERROELECTRIC LIQUID CRYSTAL DISPLAY ELEMENTS; GOOD RESPONSE | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0259346-A1 | r-1-CYAN-1-R2 -CIS-4-R1 -CYCLOHEXANE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-16 | — | — | EP | disclosed |
| EP-0260153-A2 | Cyclohexylphenylpyridazines | Chisso Corporation (JP) | 1988-03-16 | — | — | EP | disclosed |
| WO-1987005618-A1 | r-1-CYAN-1-R2-CIS-4-R1-CYCLOHEXANE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-24 | — | — | WO | disclosed |