Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31179905 | 0.80 | POLB (0.51) | ALDH1A1TSHRPOLBCTDSP1STAT3 | |
| SCHEMBL29426020 | 0.80 | POLB (0.51) | ALDH1A1TSHRPOLBCTDSP1STAT3 | |
| SCHEMBL30089774 | 0.79 | ALDH1A1 (0.71) | ELANEALDH1A1TSHRHSP90AA1KDM4E | |
| SCHEMBL20476536 | 0.74 | POLB (0.52) | POLBCTDSP1STAT3MEN1MAPT | |
| Phloyoside I SCHEMBL29426051 | 0.74 | POLB (0.55) | POLBCTDSP1STAT3MEN1MAPT | |
| Phlomiol SCHEMBL9057941 | 0.74 | POLB (0.55) | POLBCTDSP1STAT3MEN1MAPT | |
| SCHEMBL29425883 | 0.74 | ELANE (0.58) | ELANEALDH1A1TSHRHSP90AA1KDM4E | |
| SCHEMBL29425753 | 0.74 | ELANE (0.58) | ELANEALDH1A1TSHRHSP90AA1KDM4E | |
| SCHEMBL29425860 | 0.72 | ALDH1A1 (0.49) | ALDH1A1TSHRPOLBCTDSP1STAT3 | |
| SCHEMBL29425870 | 0.71 | MAPT (0.48) | ALDH1A1TSHRKDM4EGLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |