Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.78 |
| ▸ | XDH | P47989 | 2/20 | 0.57 |
| ▸ | JUN | P05412 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picroside Ii SCHEMBL24209283 | 1.00 | HSP90AA1 (0.78) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Picroside Ii SCHEMBL29367651 | 1.00 | HSP90AA1 (0.78) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Picroside Ii SCHEMBL30387354 | 1.00 | HSP90AA1 (0.78) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Picroside Ii SCHEMBL24209282 | 1.00 | HSP90AA1 (0.78) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Picroside Ii SCHEMBL29426003 | 1.00 | HSP90AA1 (0.78) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Verproside SCHEMBL31619362 | 0.92 | HSP90AA1 (0.83) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Verproside SCHEMBL2449966 | 0.92 | HSP90AA1 (0.83) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| SCHEMBL29425954 | 0.89 | HSP90AA1 (0.60) | HSP90AA1XDHJUNPOLBCTDSP1 | |
| Catalposide SCHEMBL419598 | 0.88 | HSP90AA1 (1.00) | HSP90AA1XDHPOLBCTDSP1KDM4E | |
| SCHEMBL29642990 | 0.86 | HSP90AA1 (0.85) | HSP90AA1XDHKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| CN-116350681-B | Herba Ixeritis Denticulatae extract with heart failure treating and/or preventing effects, and its preparation method and application | 珠海市藤栢医药有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119837807-A | Rhizoma picrorhizae extract and its function and use | 云南英格生物技术有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119667007-A | Method for measuring content of iridoid components | 鲁南制药集团股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119215016-A | Targeting drug-carrying system capable of penetrating blood brain barrier and preparation method and application thereof | 上海市第六人民医院 | 2024-12-31 | — | — | CN | claimed |
| WO-2024258363-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | SAHIN FIKRET (TR) | 2024-12-19 | — | — | WO | claimed |
| CN-118641676-B | Screening method of countercurrent chromatography ternary solvent system | 山东中医药大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118948874-A | Application of picroside II in preparation of products for treating pancreatic cancer | 广州医科大学附属肿瘤医院(广州市癌症防治中心) | 2024-11-15 | — | — | CN | claimed |
| CN-118697753-A | Application of picroside II in preparation of medicine for treating constipation type irritable bowel syndrome | 江苏省中医药研究院(江苏省中西医结合医院) | 2024-09-27 | — | — | CN | claimed |
| CN-118641676-A | Screening method of countercurrent chromatography ternary solvent system | 山东中医药大学 | 2024-09-13 | — | — | CN | claimed |
| CN-117871726-A | Bone clearing powder particle standard reference substance and preparation method and application thereof | 赣江中药创新中心 | 2024-04-12 | — | — | CN | claimed |
| CN-117562914-A | Application of picroside II in preparation of drug of spinal glial layer glutamatergic neurotransmitter inhibitor | 上海市精神卫生中心（上海市心理咨询培训中心） | 2024-02-20 | — | — | CN | claimed |
| CN-113773356-B | Picroside II derivative and preparation method and application thereof | 河南中医药大学 | 2024-02-02 | — | — | CN | claimed |
| CN-116990401-A | Method for analyzing three-white soup ingredients by using ultrahigh resolution liquid chromatography-mass spectrometry technology | 安徽中医药大学 | 2023-11-03 | — | — | CN | claimed |
| CN-116350681-A | Herba Ixeritis Denticulatae extract, and its preparation method and application | 珠海市藤栢医药有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116102601-A | Separation preparation method of picroside II | 山东新时代药业有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-112946139-B | Fingerprint spectrum of rhizoma picrorhizae medicinal preparation, and establishing method and application thereof | 华润三九医药股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-114432330-A | Application of picroside II in preparing medicine for preventing and treating inflammatory bowel disease | 贵州大学 | 2022-05-06 | — | — | CN | claimed |
| WO-2026086871-A1 | ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING | Centre for Translational Stem Cell Biology Limited (CN) | 2026-04-30 | — | — | WO | disclosed |
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |