Catalposide

Catalposide

SCHEMBL419598

O=C(O[C@H]1[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 9/20 1.00
▸ XDH P47989 2/20 0.70
▸ POLB P06746 1/20 0.42
▸ CTDSP1 Q9GZU7 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ TYR P14679 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Verproside SCHEMBL31619362 0.91 HSP90AA1 (0.83) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Verproside SCHEMBL2449966 0.91 HSP90AA1 (0.83) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL29425971 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL29426003 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL29367651 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL24209283 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL24209282 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Picroside Ii SCHEMBL30387354 0.88 HSP90AA1 (0.78) HSP90AA1XDHPOLBCTDSP1L3MBTL1
Specioside SCHEMBL29426185 0.86 HSP90AA1 (1.00) HSP90AA1XDHKDM4EGLACYP3A4
SCHEMBL420373 0.84 HSP90AA1 (0.73) HSP90AA1XDHPOLBCTDSP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125719-A1 VERONICA UNDULATA EXTRACT AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 珠海市藤栢医药有限公司 2023-07-06 — — WO claimed
CN-116350681-A Herba Ixeritis Denticulatae extract, and its preparation method and application 珠海市藤栢医药有限公司 2023-06-30 — — CN claimed
CN-115444855-A Pharmaceutical composition for treating ulcerative colitis and application thereof 牡丹江医学院附属红旗医院 2022-12-09 — — CN claimed
EP-3498287-A1 A PURIFIED EXTRACT (ATC2) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT, THE PREPARATION THEREOF, AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION, ALLERGY AND ASTHMA Yungjin Pharmaceutical Co., Ltd. (KR) 2019-06-19 — — EP claimed
CN-105963312-B Purified extract, preparation method and the composition comprising the extract separated from the Veronica of northeast 永进药品株式会社 2019-05-28 — — CN claimed
EP-3019182-B1 THE COMPOSITION COMPRISING A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT OR THE COMPOUNDS ISOLATED THEREFROM, AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF YUNGJIN PHARMACEUTICAL CO LTD (KR) 2019-03-13 — — EP claimed
EP-2941263-B1 A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT, THE PREPARATION THEREOF, AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION, ALLERGY AND ASTHMA YUNGJIN PHARMACEUTICAL CO LTD (KR) 2019-01-30 — — EP claimed
US-9999646-B2 Method of treating inflammation, allergy and asthma with a purified extract (ATC1) isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient YUNGJIN PHARMACEUTICAL CO., LTD (KR) 2018-06-19 — — US claimed
US-9675658-B2 Method of treating inflammation, allergy and asthma with a purified extract (ATC2) isolated from Pseudolysimachion rotundam var. subintegrum containing abundant amount of active ingredient YUNGJIN PHARMACEUTICAL CO., LTD (KR) 2017-06-13 — — US claimed
CN-105120880-B The compound for comprising the purified extract from the Veronica of northeast separate containing a large amount of active components or from this separate is used as preventing or treating composition of active component of chronic obstructive pulmonary disease and application thereof 永进药品株式会社 2017-06-13 — — CN claimed
CN-105120880-A The composition comprising a purified extract isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom, as an active ingredient for preventing or treating chronic obstructive pulmonary disease and the use thereof YUNGJIN PHARMACEUTICAL CO LTD 2015-12-02 — — CN claimed
EP-2941263-A1 A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT, THE PREPARATION THEREOF, AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION, ALLERGY AND ASTHMA Yungjin Pharmaceutical Co., Ltd. (KR) 2015-11-11 — — EP claimed
CN-104822386-A Purified extract isolated from Veronica officinalis containing a large amount of active ingredients, its preparation and composition for preventing or treating inflammation, allergy and asthma comprising the same as active ingredient YUNGJIN PHARMACEUTICAL CO LTD 2015-08-05 — — CN claimed
WO-2014168413-A1 THE COMPOSITION COMPRISING A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT OR THE COMPOUNDS ISOLATED THEREFROM, AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF YUNGJIN PHARMACEUTICAL CO., LTD. (KR) 2014-10-16 — — WO claimed
WO-2014104672-A1 A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT, THE PREPARATION THEREOF, AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION, ALLERGY AND ASTHMA YUNGJIN PHARMACEUTICAL CO., LTD. (KR) 2014-07-03 — — WO claimed
CN-102633849-A Preparation method and anticancer use of iridoid catalpa glycosides INST BOTANY JIANGSU PROVINCE & CAS 2012-08-15 — — CN claimed
CN-100522983-C Medical use of catalpol and its homologs HESHENG LUO (CN) 2009-08-05 — — CN claimed
CN-101250205-A Catalpol and use of its derivatives in preparation of medicine controlling cerebrovascular disease PENG XIE (CN) 2008-08-27 — — CN claimed
CN-1666992-A Medical use of catalpol and its homologs LUO HESHENG (CN) 2005-09-14 — — CN claimed
WO-2003047599-A1 AN ANTIINFLAMMATORY COMPOSITION CONTAINING CATALPOSIDE ISOLATED FROM STEM BARK OF CATALPA OVATA CHUNG HUN-TAEG (KR) 2003-06-12 — — WO claimed
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