SCHEMBL29426048

SCHEMBL29426048

C=C1[C@H]2[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C(C(=O)O)[C@H]2C[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.63
▸ STAT3 P40763 12/20 0.51
▸ PTPN1 P18031 3/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30289923 0.89 STAT3 (0.66) MAPTSTAT3MEN1KMT2A
SCHEMBL29425890 0.83 STAT3 (0.46) MAPTSTAT3PTPN1
Ixoside SCHEMBL29474997 0.82 MAPT (0.63) MAPTSTAT3PTPN1MEN1KMT2A
SCHEMBL31338951 0.79 MAPT (0.63) MAPTSTAT3PTPN1MEN1KMT2A
Geniposidic Acid SCHEMBL227010 0.79 PTPN1 (0.70) MAPTSTAT3PTPN1
SCHEMBL29425885 0.79 MAPT (0.63) MAPTSTAT3PTPN1MEN1KMT2A
SCHEMBL29351043 0.79 MAPT (0.71) MAPTSTAT3MEN1KMT2A
SCHEMBL22397687 0.78 MAPT (0.69) MAPTSTAT3MEN1KMT2A
Loganic Acid SCHEMBL31179995 0.77 MAPT (1.00) MAPTSTAT3MEN1KMT2A
Loganic Acid SCHEMBL29426077 0.77 MAPT (1.00) MAPTSTAT3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788869-B Preparation method of four iridoid glycoside compounds 深圳市人民医院 2023-04-28 — — CN claimed
CN-116492356-B Application of gardenoside in preparation of medicament for preventing or treating depression 中国人民解放军空军军医大学 2025-05-27 — — CN disclosed
CN-116492356-A Application of gardenoside in preparation of medicament for preventing or treating depression 中国人民解放军空军军医大学 2023-07-28 — — CN disclosed
CN-109549958-B Composition for treating hormone-dependent dermatitis and preparation method thereof 上海松皓生物科技有限公司 2023-07-21 — — CN disclosed
CN-116096242-A Bitter blocking agents and related methods of use 科纳根公司 2023-05-09 — — CN disclosed
CN-113788869-B Preparation method of four iridoid glycoside compounds 深圳市人民医院 2023-04-28 — — CN disclosed
CN-111732619-B Iridoid glycoside compound and preparation method and application thereof 江苏康缘药业股份有限公司 2022-04-19 — — CN disclosed
EP-3409766-B1 AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS N ZYME BIOTEC GMBH (DE) 2022-03-09 — — EP disclosed
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