Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 6/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739485 | 1.00 | CHRM4 (0.34) | CHRM4CHRM1CHRM2ABHD6CNR2 | |
| SCHEMBL26631009 | 1.00 | CHRM4 (0.34) | CHRM4CHRM1CHRM2ABHD6CNR2 | |
| SCHEMBL26750427 | 0.89 | CHRM2 (0.33) | CHRM4CHRM1CHRM2DGAT2PIK3R1 | |
| SCHEMBL26631463 | 0.87 | CHRM4 (0.32) | CHRM4CHRM1CHRM2ABHD6DGAT2 | |
| SCHEMBL30503568 | 0.87 | CHRM4 (0.32) | CHRM4CHRM1CHRM2ABHD6DGAT2 | |
| SCHEMBL29426752 | 0.84 | CHRM4 (0.34) | CHRM4CHRM1CHRM2ABHD6CNR2 | |
| SCHEMBL26631081 | 0.84 | CHRM4 (0.34) | CHRM4CHRM1CHRM2ABHD6CNR2 | |
| SCHEMBL26739483 | 0.84 | CHRM4 (0.34) | CHRM4CHRM1CHRM2ABHD6CNR2 | |
| SCHEMBL25412820 | 0.83 | PDE4D (0.37) | CNR2PIK3CDRORC | |
| SCHEMBL29427106 | 0.83 | PDE4D (0.37) | CNR2PIK3CDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-B1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-09 | — | — | EP | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| WO-2022063784-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-31 | — | — | WO | claimed |