Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631463 | 1.00 | CHRM4 (0.32) | CHRM4CHRM1FFAR4PIK3CDITGB3 | |
| SCHEMBL29427106 | 0.88 | PDE4D (0.37) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25412820 | 0.88 | PDE4D (0.37) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26750427 | 0.87 | CHRM2 (0.33) | CHRM4CHRM1DGAT2CHRM2 | |
| SCHEMBL26739485 | 0.87 | CHRM4 (0.34) | CHRM4CHRM1PIK3CDDGAT2FAAH | |
| SCHEMBL26631009 | 0.87 | CHRM4 (0.34) | CHRM4CHRM1PIK3CDDGAT2FAAH | |
| SCHEMBL29426927 | 0.87 | CHRM4 (0.34) | CHRM4CHRM1PIK3CDDGAT2FAAH | |
| SCHEMBL26631421 | 0.84 | FFAR4 (0.32) | FFAR4ITGB3ITGA2BFAAHMGLL | |
| SCHEMBL30503578 | 0.82 | HCRTR1 (0.31) | FFAR4FAAHMGLLABHD6 | |
| SCHEMBL26631337 | 0.82 | HCRTR1 (0.31) | FFAR4FAAHMGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |