Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942704 | 0.86 | FAP (0.51) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL2940661 | 0.84 | FAP (0.34) | FAPALDH1A1 | |
| SCHEMBL4274931 | 0.82 | FAP (0.51) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL2910508 | 0.81 | FAP (0.51) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL2939154 | 0.79 | FAP (0.51) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL2906659 | 0.75 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1ADORA2BPI4KA | |
| SCHEMBL2906656 | 0.74 | ADORA2A (0.55) | ADORA2AADORA1ALDH1A1ADORA2BPI4KA | |
| SCHEMBL2939158 | 0.74 | FAP (0.50) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL13328650 | 0.73 | CYP3A4 (0.48) | FAPADORA2AADORA1ALDH1A1CYP3A4 | |
| SCHEMBL4265957 | 0.73 | FAP (0.53) | FAPADORA2AADORA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |