Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.34 |
| ▸ | CDK2 | P24941 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270182 | 0.90 | FAP (0.37) | FAPCCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL2990364 | 0.87 | FAP (0.35) | FAPPDE3ACCNE1CDK2KDM4E | |
| SCHEMBL2942826 | 0.86 | FAP (0.35) | FAPCCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL3292459 | 0.82 | FAP (0.36) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL5943180 | 0.82 | FAP (0.33) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL4267905 | 0.80 | FAP (0.36) | FAPCCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL4274826 | 0.80 | FAP (0.36) | FAPCCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL4273076 | 0.79 | HPRT1 (0.31) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2999182 | 0.78 | CCNE1 (0.36) | CCNE1CDK2CDK1CCNB1SLC29A1 | |
| SCHEMBL4266050 | 0.77 | CYP2C19 (0.33) | CCNE1CDK2CDK1CCNB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |