Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424981 | 0.84 | FDPS (0.39) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL372352 | 0.84 | SMN1; SMN2 (0.38) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL29434929 | 0.84 | SMN1; SMN2 (0.38) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| Lithium SCHEMBL29973484 | 0.82 | SMN1; SMN2 (0.37) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL2934584 | 0.82 | FDPS (0.40) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL29395782 | 0.81 | SMN1; SMN2 (0.46) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL30193788 | 0.80 | FDPS (0.33) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL3678674 | 0.80 | SMN1; SMN2 (0.39) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL422564 | 0.79 | FDPS (0.50) | FDPSSMN1; SMN2MEN1APAF1NPC1 | |
| SCHEMBL2691328 | 0.79 | FDPS (0.33) | FDPSSMN1; SMN2MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094323-A2 | METHODS AND COMPOSITIONS FOR MODULATING HORMONE LEVELS | Ligand Pharmaceuticals Incorporated (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015108988-A2 | METHODS AND COMPOSITIONS FOR MODULATING HORMONE LEVELS | LIGAND PHARMACEUTICALS, INC. (US) | 2015-07-23 | — | — | WO | disclosed |
| EP-2222636-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF | Ligand Pharmaceuticals Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009082437-A9 | SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2009082437-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-07-02 | — | — | WO | disclosed |