SCHEMBL29428907

SCHEMBL29428907

N=C(N)c1ccc(-c2ccc(-c3cc4ccc(C(=N)N)cc4[nH]3)cc2)cc1

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 1/20 0.81
▸ PRMT3 O60678 1/20 0.81
▸ CARM1 Q86X55 1/20 0.81
▸ EHMT2 Q96KQ7 1/20 0.81
▸ PRMT6 Q96LA8 1/20 0.81
▸ PRMT1 Q99873 1/20 0.81
▸ WDR77 Q9BQA1 1/20 0.81
▸ PRMT8 Q9NR22 1/20 0.81
▸ PRMT7 Q9NVM4 1/20 0.81
▸ F2 P00734 2/20 0.61
▸ F10 P00742 1/20 0.56
▸ PLG P00747 1/20 0.56
▸ PLAU P00749 1/20 0.56
▸ PRSS1 P07477 1/20 0.56
▸ ASIC3 Q9UHC3 1/20 0.55
▸ CASP3 P42574 1/20 0.53
▸ SENP8 Q96LD8 1/20 0.53
▸ SENP7 Q9BQF6 1/20 0.53
▸ SENP6 Q9GZR1 1/20 0.53
▸ HPN P05981 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dapi SCHEMBL28176609 0.98 PRMT5 (0.83) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL29350295 0.98 PRMT5 (0.83) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL235865 0.98 PRMT5 (0.83) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL30442885 0.97 PRMT5 (0.81) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL2464378 0.97 PRMT5 (0.81) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL94350 0.97 PRMT5 (0.81) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL14854556 0.97 PRMT5 (0.81) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL3492008 0.95 PRMT5 (0.79) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL1609032 0.95 PRMT5 (0.79) PRMT5PRMT3CARM1EHMT2PRMT6
Dapi SCHEMBL15966967 0.95 PRMT5 (0.79) PRMT5PRMT3CARM1EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233645-A1 METHOD FOR TRAINING A SYSTEM ADAPTED FOR CLASSIFYING A BIOSENSOR SIGNAL CORRESPONDING TO A CELL, AND SYSTEM TRAINED BY THEREOF HUN-REN ENERGIATUDOMÁNYI KUTATÓKÖZPONT (HU) 2025-11-13 — — WO disclosed
WO-2025064402-A1 METHOD FOR TREATING SICKLE CELL DISEASE BY TARGETING SENESCENT CELLS ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2025-03-27 — — WO disclosed
WO-2023007044-A1 COMPOSITE MATERIAL OF POLYACRYLONITRILE AND GRAPHENE NANOPLATELETS, OBTAINMENT METHOD AND USE AS A SUBSTRATE FOR IN VITRO CULTURES OF CANCER CELLS. FUNDACIÓN INSTITUTO DE INVESTIGACIÓN MARQUÉS DE VALDECILLA IDIVAL (ES) 2023-02-02 — — WO disclosed
EP-3962599-A1 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR STABILIZING AGENTS VIB VZW (BE) 2022-03-09 — — EP disclosed
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