SCHEMBL29429151

SCHEMBL29429151

CC(=O)n1c2ccc(I)cc2c2cc(I)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
LMNA P02545 3/20 0.49
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
DNMT1 P26358 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPY5R Q15761 1/20 0.36
BAZ2B Q9UIF8 1/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 1/20 0.36
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872231 1.00 POLB (0.53) POLBLMNAGABRG2GABRB3GABRA5
SCHEMBL1689491 0.91 POLB (0.70) POLBLMNAGABRG2GABRB3GABRA5
SCHEMBL9982710 0.84 POLB (0.53) POLBLMNAGABRG2GABRB3GABRA5
SCHEMBL28465025 0.76 POLB (0.53) POLBLMNAALDH1A1KDM4EHPGD
SCHEMBL29865552 0.76 BAZ2B (0.56) POLBLMNAALDH1A1KDM4EHPGD
SCHEMBL10064601 0.75 GABRG2 (0.72) GABRG2GABRB3GABRA5DNMT1
SCHEMBL4848329 0.74 SRC (0.60) LMNAALDH1A1HPGDDNMT1MAPT
SCHEMBL6378148 0.73 NOTUM (0.38) POLBALDH1A1KDM4EHPGDHSD17B10
SCHEMBL29582349 0.72 POLB (0.48) POLBLMNAGABRG2GABRB3GABRA5
SCHEMBL21122012 0.72 POLB (0.48) POLBLMNAGABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137293-A2 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. (US) 2025-06-26 WO disclosed
CN-119823106-A Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2025-04-15 CN disclosed
CN-119631160-A Stripping agent composition for light irradiation stripping, laminate, and method for producing processed semiconductor substrate 日产化学株式会社 2025-03-14 CN disclosed
US-20250043176-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING PYRENE GROUP AND ORGANIC LIGHT-EMITTING DIODES USING THE SAME YUAN ZE UNIVERSITY (TW) 2025-02-06 US disclosed
CN-114144520-B Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2024-12-13 CN disclosed
CN-111771001-B Enhanced nucleic acid polymerization by aromatic compounds F·霍夫曼-罗氏股份公司 2024-09-06 CN disclosed
CN-118507421-A Laminate containing novolac resin as release layer 日产化学株式会社 2024-08-16 CN disclosed
CN-111316401-B Laminate containing novolac resin as release layer 日产化学株式会社 2024-08-02 CN disclosed
CN-117882172-A Adhesive composition, laminate, and method for producing processed semiconductor substrate 日产化学株式会社 2024-04-12 CN disclosed
CN-109075060-B Method for manufacturing semiconductor substrate having group III nitride compound layer 日产化学株式会社 2024-03-29 CN disclosed
CN-117716474-A Method for producing laminate and kit of adhesive composition 日产化学株式会社 2024-03-15 CN disclosed
CN-116997861-A Composition for forming resist underlayer film 日产化学株式会社 2023-11-03 CN disclosed
CN-116635442-A Composition for forming resist underlayer film 日产化学株式会社 2023-08-22 CN disclosed
CN-116235112-A Composition for forming resist underlayer film comprising fluoroalkyl group-containing organic acid or salt thereof 日产化学株式会社 2023-06-06 CN disclosed
CN-116157898-A Laminate, stripper composition, and method for producing processed semiconductor substrate 日产化学株式会社 2023-05-23 CN disclosed
WO-2022065374-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF 日産化学株式会社 2022-03-31 WO disclosed
CN-114144520-A Enhanced nucleic acid polymerization by aromatic compounds 斯特拉托斯基因公司 2022-03-04 CN disclosed