Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 17/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657184 | 1.00 | TGFBR1 (1.00) | TGFBR1EGFRERBB3CA12CA1 | |
| SCHEMBL373618 | 1.00 | TGFBR1 (1.00) | TGFBR1EGFRERBB3CA12CA1 | |
| SCHEMBL4174543 | 0.90 | TGFBR1 (0.82) | TGFBR1 | |
| SCHEMBL3953868 | 0.89 | TGFBR1 (0.79) | TGFBR1ROCK1 | |
| SCHEMBL4172942 | 0.88 | TGFBR1 (0.79) | TGFBR1 | |
| SCHEMBL4168353 | 0.87 | TGFBR1 (0.77) | TGFBR1CCNA2CDK2 | |
| SCHEMBL3953297 | 0.86 | TGFBR1 (0.75) | TGFBR1EGFRERBB3CA1CA2 | |
| SCHEMBL3946083 | 0.85 | TGFBR1 (0.73) | TGFBR1CA12CA1CA2 | |
| SCHEMBL4183440 | 0.85 | TGFBR1 (0.73) | TGFBR1 | |
| SCHEMBL3948134 | 0.84 | TGFBR1 (0.72) | TGFBR1EGFRERBB3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545871-B2 | Culture container for culturing epithelial cells and use thereof | KEIO UNIVERSITY (JP) | 2026-02-10 | — | — | US | disclosed |
| US-20250283049-A1 | AGENT FOR CULTURING ORGANOID IN ABSENCE OF EXTRACELLULAR MATRIX | UNIV KEIO (JP) | 2025-09-11 | — | — | US | disclosed |
| EP-4596677-A1 | DRUG FOR CULTURING ORGANOID IN ABSENCE OF EXTRACELLULAR MATRIX | Keio University (JP) | 2025-08-06 | — | — | EP | disclosed |
| CN-116716236-B | Construction method and application of cervical cancer organoids | 重庆大学附属肿瘤医院 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024171957-A1 | TRANSPLANTATION OF PITUITARY HORMONE-PRODUCING CELLS | 国立大学法人東海国立大学機構 | 2024-08-22 | — | — | WO | disclosed |
| CN-116555165-B | Cervical cancer organoid culture medium and application thereof | 重庆大学附属肿瘤医院 | 2024-08-06 | — | — | CN | disclosed |
| CN-118318033-A | Cell aggregate comprising pituitary hormone-producing cells and method for producing the same | 住友制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118043447-A | Method for preparing cell population containing pituitary tissue and cell population | 住友化学株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-111334463-B | Cell culture medium for organoid culture, culture method and organoid | 学校法人庆应义塾 | 2024-02-20 | — | — | CN | disclosed |
| CN-111349604-B | Cell culture medium for organoid culture, culture method and organoid | 学校法人庆应义塾 | 2023-12-12 | — | — | CN | disclosed |
| CN-116716236-A | Construction method and application of cervical cancer organoids | 重庆大学附属肿瘤医院 | 2023-09-08 | — | — | CN | disclosed |
| CN-116555165-A | Cervical cancer organoid culture medium and application thereof | 重庆大学附属肿瘤医院 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023054396-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | 住友化学株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023054395-A1 | CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME | 住友ファーマ株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023042901-A1 | PRODUCTION OF ORGANOID DERIVED FROM CTC OF SMALL CELL LUNG CANCER PATIENT, AND IGF1R INHIBITOR AS A MOLECULAR TARGET DRUG FOR SMALL CELL LUNG CANCER | 慶應義塾 | 2023-03-23 | — | — | WO | disclosed |
| WO-2023277135-A1 | METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |
| CN-109415680-B | Cell culture medium for organoid culture, culture method, and organoid | 学校法人庆应义塾 | 2022-08-16 | — | — | CN | disclosed |
| CN-109072179-B | Cell culture medium, culture method and organoid | 学校法人庆应义塾 | 2022-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545871-B2 | Culture container for culturing epithelial cells and use thereof | ATM, EPCAM, DDR1 | TGFBR1 1148/4885EGFR 17/4885ERBB3 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.