Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.60 |
| ▸ | TNF | P01375 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682269 | 1.00 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL30025066 | 0.84 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL30025359 | 0.84 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682197 | 0.84 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682294 | 0.84 | ADORA2B (0.60) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL19601317 | 0.81 | ADORA2B (0.53) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682296 | 0.78 | ADORA2B (0.59) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL18819716 | 0.78 | ADORA2B (0.62) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682172 | 0.77 | ADORA2B (0.58) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL17682262 | 0.77 | ADORA2B (0.49) | ADORA2BTNFUSP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |
| EP-3205652-B1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG RAYNOVENT BIOTECH CO LTD (CN) | 2022-03-09 | — | — | EP | disclosed |