Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641963 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL10739933 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL2554946 | 0.97 | — | — | |
| SCHEMBL1170726 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL7153830 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL9715324 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL10743836 | 0.95 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL13485232 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRBMAPK1TDP1 | |
| SCHEMBL2422200 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL16361118 | 0.84 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRBMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993549-A | Immunoconjugates targeting HER2 | 博尔特生物治疗药物有限公司 | 2022-01-28 | — | — | CN | disclosed |