Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395242 | 0.92 | OTUD7B (0.37) | OTUD7BGRIN1GRIN2AGRIN2BSMN1; SMN2 | |
| SCHEMBL24230501 | 0.88 | OTUD7B (0.39) | OTUD7B | |
| SCHEMBL20788754 | 0.85 | OTUD7B (0.33) | OTUD7BGRIN1GRIN2A | |
| SCHEMBL24230502 | 0.83 | OTUD7B (0.41) | OTUD7B | |
| SCHEMBL21584978 | 0.78 | — | — | |
| SCHEMBL24230500 | 0.76 | — | — | |
| SCHEMBL31580651 | 0.73 | GAA (0.34) | OTUD7BGRIN1GRIN2A | |
| SCHEMBL25238524 | 0.73 | OTUD7B (0.37) | OTUD7BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1429855 | 0.73 | OTUD7B (0.46) | OTUD7BGRIN1GRIN2AGRIN2B | |
| SCHEMBL19659532 | 0.72 | OTUD7B (0.42) | OTUD7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072397-A | Heteroaryl aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-02-18 | — | — | CN | claimed |
| CN-114072397-B | Heteroaryl aminopyrimidinamide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-114072397-A | Heteroaryl aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-02-18 | — | — | CN | disclosed |