Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485773 | 0.97 | LTA4H (0.62) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828595 | 0.97 | LTA4H (0.62) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29440485 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828625 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828268 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29829233 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828893 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828703 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828853 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA | |
| SCHEMBL29828574 | 0.95 | KDM4E (0.64) | LTA4HKMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204092-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. (US) | 2023-07-05 | — | — | EP | claimed |
| WO-2022046644-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. (US) | 2022-03-03 | — | — | WO | claimed |
| US-20250059261-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. | 2025-02-20 | — | — | US | disclosed |
| US-12195524-B2 | Multi-specific antigen binding molecules targeting HIV and methods of use | GILEAD SCIENCES, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| EP-4204092-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20230056252-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2022046644-A1 | MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE | GILEAD SCIENCES, INC. (US) | 2022-03-03 | — | — | WO | disclosed |