SCHEMBL29430129

SCHEMBL29430129

CC(C)C[C@@H](NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CS)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](CS)NC(=O)[C@H]1CCCN1C(=O)[C@H](N)Cc1cnc[nH]1)C(=O)NCC(=O)N[C@H](CCCCN)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CXCR4 P61073 11/20 0.74
▸ NPY1R P25929 1/20 0.63
▸ NPY2R P49146 1/20 0.63
▸ NPY4R P50391 1/20 0.63
▸ NPY5R Q15761 1/20 0.63
▸ GNRHR P30968 1/20 0.60
▸ GLP1R P43220 6/20 0.59
▸ MC4R P32245 1/20 0.58
▸ MC5R P33032 1/20 0.58
▸ MC3R P41968 1/20 0.58
▸ MC1R Q01726 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860804 1.00 CXCR4 (0.74) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL31650839 0.88 CXCR4 (0.68) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29635486 0.87 CXCR4 (0.73) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29437879 0.87 CXCR4 (0.91) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29437878 0.87 CXCR4 (0.91) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29421992 0.86 CXCR4 (0.66) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29689766 0.86 CXCR4 (0.66) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29358032 0.86 CXCR4 (0.65) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL31656488 0.85 NPY1R (0.66) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL30431758 0.84 C5AR1 (0.69) CXCR4GLP1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118127213-A Molecular marker primer group based on magnolia officinalis and magnolia officinalis transcriptome sequencing and application 绵阳师范学院 2024-06-04 — — CN claimed
WO-2026090160-A2 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2026-04-30 — — WO disclosed
US-20260109746-A1 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES INC (US) 2026-04-23 — — US disclosed
EP-4667499-A2 INTERLEUKIN-2-FC FUSION PROTEINS AND METHODS OF USE Gilead Sciences, Inc. (US) 2025-12-24 — — EP disclosed
EP-4232463-B1 INTERLEUKIN-2-FC FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES INC (US) 2025-09-03 — — EP disclosed
US-20240269235-A1 INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2024-08-15 — — US disclosed
CN-118127213-A Molecular marker primer group based on magnolia officinalis and magnolia officinalis transcriptome sequencing and application 绵阳师范学院 2024-06-04 — — CN disclosed
US-11896648-B2 Interleukin-2 variant proteins fused to human IgG4 Fc and uses thereof GILEAD SCIENCES, INC. (US) 2024-02-13 — — US disclosed
EP-4232463-A2 INTERLEUKIN-2-FC FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2023-08-30 — — EP disclosed
CN-114277040-B Construction method and application of efficient synthesis beta-carotene strain 江南大学 2023-08-25 — — CN disclosed
CN-114410631-B Construction method and application of high-efficiency synthesis of cembratriene-monoalcohol strain 江南大学 2023-08-08 — — CN disclosed
EP-4204092-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2023-07-05 — — EP disclosed
CN-109069577-B D-peptide inhibitors of HIV entry and methods of use 纳维根公司 2022-08-19 — — CN disclosed
CN-114410631-A Construction method and application of efficient synthesis of cembratriene-alcohol strain 江南大学 2022-04-29 — — CN disclosed
US-20220125884-A1 INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2022-04-28 — — US disclosed
WO-2022087149-A2 INTERLEUKIN-2-FC FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-04-28 — — WO disclosed
CN-114277040-A Construction method and application of bacterial strain for efficiently synthesizing beta-carotene 江南大学 2022-04-05 — — CN disclosed
WO-2022046644-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109746-A1 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE IL15, IL15RA, CD4 CXCR4 968/4885NPY1R 469/4885NPY2R 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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