SCHEMBL29635486

SCHEMBL29635486

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CXCR4 P61073 14/20 0.73
▸ GNRHR P30968 1/20 0.62
▸ MC4R P32245 2/20 0.62
▸ MC5R P33032 2/20 0.62
▸ MC3R P41968 2/20 0.62
▸ MC1R Q01726 2/20 0.62
▸ NPY1R P25929 1/20 0.61
▸ NPY2R P49146 1/20 0.61
▸ NPY4R P50391 1/20 0.61
▸ NPY5R Q15761 1/20 0.61
▸ CALCA P06881 1/20 0.59
▸ PTH1R Q03431 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860804 0.87 CXCR4 (0.74) CXCR4GNRHRMC4RMC5RMC3R
SCHEMBL29430129 0.87 CXCR4 (0.74) CXCR4GNRHRMC4RMC5RMC3R
SCHEMBL15147203 0.86 F2 (0.60) CXCR4MC4RMC5RMC3RMC1R
SCHEMBL29462904 0.86 CXCR4 (0.83) CXCR4GNRHR
SCHEMBL29491173 0.85 C5AR1 (0.65) CXCR4GNRHR
SCHEMBL30646334 0.85 CXCR4 (0.63) CXCR4NPY1RNPY2RNPY4RNPY5R
SCHEMBL29421992 0.84 CXCR4 (0.66) CXCR4GNRHRMC4RMC5RMC3R
SCHEMBL29689766 0.84 CXCR4 (0.66) CXCR4GNRHRMC4RMC5RMC3R
SCHEMBL30633418 0.84 DPP3 (0.60) CXCR4
SCHEMBL31278597 0.83 CCKBR (0.58) CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264811-A1 COMPOSITION AND METHODS FOR CONTROLLED RECRUITMENT OF ANALYTES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-12-26 — — WO claimed
EP-3467509-B1 CNS ANTIGEN-SPECIFIC B CELL, T CELL AND ANTIBODY ASSAYS AND THEIR USES IN DIAGNOSIS AND TREATMENT OF MULTIPLE SCLEROSIS CELLULAR TECH LTD (US) 2025-11-26 — — EP disclosed
US-20250288654-A1 TOLERANCE-INDUCING CONSTRUCTS AND COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF IMMUNE DISORDERS Nykode Therapeutics ASA (NO) 2025-09-18 — — US disclosed
EP-4615980-A1 CO-EXPRESSION OF CONSTRUCTS AND POLYPEPTIDES Nykode Therapeutics ASA (NO) 2025-09-17 — — EP disclosed
US-20250276981-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. 2025-09-04 — — US disclosed
US-20250195632-A1 TOLERANCE-INDUCING CONSTRUCTS AND COMPOSITION AND THEIR USE FOR THE TREATMENT OF IMMUNE DISORDERS Nykode Therapeutics ASA (NO) 2025-06-19 — — US disclosed
EP-4536658-A1 1,8-NAPHTHYRIDIN-2-ONE HETEROBIFUNCTIONAL BCL6 DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 — — EP disclosed
EP-4536649-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 — — EP disclosed
EP-4536650-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 — — EP disclosed
WO-2025049968-A1 TRICYCLIC QUINOLONE AND 1,8-NAPHTHYRIDIN-2-ONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 — — WO disclosed
CN-110064049-B Peptide conjugate particles 西北大学 2024-02-09 — — CN disclosed
CN-117377483-A Tolerance-inducing constructs and compositions and their use in the treatment of immune disorders 耐考德治疗股份有限公司 2024-01-09 — — CN disclosed
CN-117355326-A Co-expression of constructs and immunosuppressive compounds 耐考德治疗股份有限公司 2024-01-05 — — CN disclosed
WO-2023244918-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 — — WO disclosed
WO-2023244917-A1 1,8-NAPHTHYRIDIN-2-ONE HETEROBIFUNCTIONAL BCL6 DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 — — WO disclosed
WO-2023240038-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-14 — — WO disclosed
WO-2022238395-A1 TOLERANCE-INDUCING CONSTRUCTS AND COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF IMMUNE DISORDERS Nykode Therapeutics ASA (NO) 2022-11-17 — — WO disclosed
WO-2022238432-A2 CO-EXPRESSION OF CONSTRUCTS AND IMMUNOINHIBITORY COMPOUNDS Nykode Therapeutics ASA (NO) 2022-11-17 — — WO disclosed
WO-2022238402-A1 TOLERANCE-INDUCING CONSTRUCTS AND COMPOSITION AND THEIR USE FOR THE TREATMENT OF IMMUNE DISORDERS Nykode Therapeutics ASA (NO) 2022-11-17 — — WO disclosed
US-11340224-B2 Whole brain lysate antigen-specific memory B cell and antibody assays in multiple sclerosis CELLULAR TECHNOLOGY LIMITED (US) 2022-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276981-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS BCL6, BCL6B, BCOR CXCR4 3203/4885GNRHR 3591/4885MC4R 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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