Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 19/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 18/20 | 0.59 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500648 | 0.83 | CCNT1 (0.51) | CDK9CCNT1 | |
| SCHEMBL17534989 | 0.82 | CCNT1 (0.76) | CDK9CCNT1 | |
| SCHEMBL15586779 | 0.82 | CCNT1 (0.52) | CDK9CCNT1 | |
| SCHEMBL5663907 | 0.81 | CCNT1 (0.53) | CDK9CCNT1 | |
| SCHEMBL14500649 | 0.80 | CCNT1 (0.67) | CDK9CCNT1 | |
| SCHEMBL17906588 | 0.79 | CCNT1 (0.49) | CDK9CCNT1 | |
| SCHEMBL16546258 | 0.79 | CDK9 (0.48) | CDK9CCNT1CDC7PIM1 | |
| SCHEMBL2085336 | 0.78 | CDK9 (0.47) | CDK9CCNT1CDC7PIM1 | |
| SCHEMBL5661424 | 0.78 | CCNT1 (0.65) | CDK9CCNT1 | |
| SCHEMBL5665564 | 0.78 | CDK9 (0.66) | CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051568-A1 | SUBSTITUTED 4-PIPERIDINYL-PYRROLO[2,3-B]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2022-03-10 | — | — | WO | disclosed |