Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290849 | 1.00 | KDM4E (1.00) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| Hydrochloric Acid SCHEMBL28576259 | 0.98 | KDM4E (0.95) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| Hydrochloric Acid SCHEMBL28576260 | 0.98 | KDM4E (0.95) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| SCHEMBL11510669 | 0.88 | KDM4E (0.78) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| SCHEMBL329569 | 0.76 | MAPT (0.61) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL30987223 | 0.75 | MAPT (0.60) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL28563540 | 0.75 | MAPT (0.60) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11704181 | 0.73 | MAPT (0.57) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| SCHEMBL6825021 | 0.73 | MAPT (0.57) | KDM4EMAPTALDH1A1HSD17B10TLR4 | |
| SCHEMBL3995672 | 0.73 | MAPT (0.57) | KDM4EMAPTALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403800-A | Compounds and their use as LPAR5 antagonists | 艾美斐生物医药科技(上海)有限公司 | 2025-02-07 | — | — | CN | disclosed |
| EP-4486742-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUNOPHAGE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2025-01-08 | — | — | EP | disclosed |
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |
| CN-115872947-B | Benzisothiazole benzamide compound or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117771910-A | Chloromethane tail gas recovery processing system | 安徽英特力工业工程技术有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117732223-A | Chloromethane tail gas recovery treatment process for BIT and BBIT chlorination reaction section | 安徽英特力工业工程技术有限公司 | 2024-03-22 | — | — | CN | disclosed |
| JP-2023136302-A | 3-AMINOBENZOISOTHIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREOF | 富士フイルム株式会社 | 2023-09-29 | — | — | JP | disclosed |
| CN-113861181-B | Polysubstituted isothiazole derivative and preparation method thereof | 云南大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-113773273-B | Benzisothiazole compound, preparation method and application thereof | 沈阳药科大学 | 2023-04-11 | — | — | CN | disclosed |
| WO-2022251359-A1 | BICYCLIC INHIBITORS OF ALK5 AND METHODS OF USE | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2022-12-01 | — | — | WO | disclosed |
| EP-3765449-A4 | AMINO-BENZOISOTHIAZOLE AND AMINO-BENZOISOTHIADIAZOLE AMIDE COMPOUNDS | Aerie Pharmaceuticals, Inc. (US) | 2022-03-30 | — | — | EP | disclosed |