Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987223 | 1.00 | MAPT (0.60) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL6964514 | 0.86 | KDM4E (0.52) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL24566449 | 0.81 | MAPT (0.47) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL330490 | 0.81 | KDM4E (0.43) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL3626867 | 0.80 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL29940995 | 0.80 | EPAS1 (0.54) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL19358934 | 0.80 | KDM4E (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11359600 | 0.80 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL3150476 | 0.80 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL29610220 | 0.78 | KDM4E (0.41) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113009042-B | 3- (1-piperazinyl) -1,2-benzisothiazole hydrochloride and analysis and detection method of related substances thereof | 海南鑫开源医药科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-112920135-A | Dimer impurity in ziprasidone hydrochloride raw material and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-113009042-B | 3- (1-piperazinyl) -1,2-benzisothiazole hydrochloride and analysis and detection method of related substances thereof | 海南鑫开源医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113009042-A | Analysis and detection method of 3- (1-piperazinyl) -1, 2-benzisothiazole hydrochloride and related substances thereof | 海南鑫开源医药科技有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-112920135-A | Dimer impurity in ziprasidone hydrochloride raw material and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-06-08 | — | — | CN | disclosed |