Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAX | Q07812 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.97 |
| ▸ | TP53 | P04637 | 1/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.97 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | RAD52 | P43351 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PER2 | O15055 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991749 | 1.00 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL610221 | 1.00 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL29716701 | 1.00 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL609012 | 1.00 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL609455 | 1.00 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL31457408 | 0.99 | MAPT (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL31457406 | 0.99 | MAPT (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL21085183 | 0.99 | MAPT (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL30102393 | 0.99 | MAPT (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL30102390 | 0.99 | MAPT (1.00) | BAXMAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |