SCHEMBL29991749

SCHEMBL29991749

OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BAX Q07812 2/20 1.00
MAPT P10636 2/20 0.97
TP53 P04637 1/20 0.97
CYP3A4 P08684 1/20 0.97
ALOX15 P16050 1/20 0.97
MAPK1 P28482 1/20 0.97
RAD52 P43351 3/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
DNM1 Q05193 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
IDO1 P14902 1/20 0.55
NLRP1 Q9C000 1/20 0.53
P2RX3 P56373 1/20 0.52
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
POLB P06746 1/20 0.48
PER2 O15055 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610221 1.00 BAX (1.00) BAXMAPTTP53CYP3A4ALOX15
SCHEMBL29716701 1.00 BAX (1.00) BAXMAPTTP53CYP3A4ALOX15
SCHEMBL29432619 1.00 BAX (1.00) BAXMAPTTP53CYP3A4ALOX15
SCHEMBL609012 1.00 BAX (1.00) BAXMAPTTP53CYP3A4ALOX15
SCHEMBL609455 1.00 BAX (1.00) BAXMAPTTP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL31457408 0.99 MAPT (1.00) BAXMAPTTP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL31457406 0.99 MAPT (1.00) BAXMAPTTP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL21085183 0.99 MAPT (1.00) BAXMAPTTP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL30102393 0.99 MAPT (1.00) BAXMAPTTP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL30102390 0.99 MAPT (1.00) BAXMAPTTP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655258-B Compositions for cryopreservation and methods of use thereof 常青树生物科学公司 2025-03-21 CN claimed
US-12053454-B2 Compositions for cryopreservation and methods of use thereof EVERGREEN BIOSCIENCES (US) 2024-08-06 US claimed
WO-2022241417-A1 METHODS AND COMPOSITIONS FOR EXTENDING ORGAN AND TISSUE PRESERVATION THE GENERAL HOSPITAL CORPORATION (US) 2022-11-17 WO disclosed
CN-111803504-B Application of iMAC1 in preparation of product for treating cancer 军事科学院军事医学研究院生物医学分析中心 2022-11-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12053454-B2 Compositions for cryopreservation and methods of use thereof BAK1, BAX, BAD BAX 2/4885MAPT 2314/4885TP53 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.