Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 10/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2943098 | 0.99 | FFAR1 (0.45) | FFAR1FFAR4HIF1ABDKRB1ABL1 | |
| SCHEMBL3655943 | 0.77 | EPHX2 (0.46) | CNR1KMT2A | |
| SCHEMBL2949321 | 0.75 | ALOX5AP (0.53) | FFAR1FFAR4BDKRB1ALOX5APFEN1 | |
| SCHEMBL2950599 | 0.74 | BDKRB1 (0.74) | BDKRB1CNR1 | |
| SCHEMBL2948017 | 0.73 | ALOX5AP (0.54) | FFAR1FFAR4BDKRB1ALOX5APFEN1 | |
| SCHEMBL2943305 | 0.70 | FFAR1 (0.45) | FFAR1FFAR4BDKRB1ABL1ALOX5AP | |
| SCHEMBL23347204 | 0.70 | ALOX5AP (0.56) | FFAR1FFAR4ALOX5APFEN1 | |
| SCHEMBL5925998 | 0.69 | HIF1A (0.50) | HIF1AKMT2A | |
| SCHEMBL2942746 | 0.69 | BDKRB1 (0.49) | FFAR1FFAR4BDKRB1ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL2943097 | 0.69 | FFAR1 (0.44) | FFAR1FFAR4BDKRB1ABL1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |