Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312418 | 0.84 | HDAC6 (0.41) | OPRM1POLBGAAALDH1A1CYP1A2 | |
| SCHEMBL28728896 | 0.82 | MAPT (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7357436 | 0.81 | POLB (0.41) | OPRM1POLBALDH1A1CYP1A2TSHR | |
| SCHEMBL1925942 | 0.81 | POLB (0.41) | OPRM1POLBALDH1A1CYP1A2TSHR | |
| SCHEMBL1762208 | 0.81 | POLB (0.41) | OPRM1POLBALDH1A1CYP1A2TSHR | |
| SCHEMBL28679009 | 0.80 | POLB (0.44) | OPRM1POLBGAAALDH1A1CYP1A2 | |
| SCHEMBL4953723 | 0.80 | POLB (0.44) | OPRM1POLBGAAALDH1A1CYP1A2 | |
| SCHEMBL4953717 | 0.80 | POLB (0.44) | OPRM1POLBGAAALDH1A1CYP1A2 | |
| SCHEMBL13180333 | 0.80 | TAAR1 (0.55) | POLBALDH1A1TSHRTAAR1ADRA2A | |
| SCHEMBL4302479 | 0.79 | POLB (0.43) | OPRM1POLBGAAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026162-B | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-04-05 | — | — | CN | disclosed |