Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433262 | 0.84 | OPRM1 (0.44) | OPRM1GAAPOLBALDH1A1CYP1A2 | |
| SCHEMBL11031009 | 0.80 | NPC1 (0.50) | MMP1MMP3ALDH1A1 | |
| SCHEMBL10782208 | 0.80 | NPC1 (0.50) | MMP1MMP3ALDH1A1 | |
| SCHEMBL6320167 | 0.76 | NAAA (0.39) | HDAC3HDAC1HDAC2MMP1MMP3 | |
| SCHEMBL28420962 | 0.75 | EPOR (0.37) | HDAC6HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL3342836 | 0.75 | ALDH1A1 (0.45) | HDAC6HDAC1GAAMMP1MMP3 | |
| SCHEMBL3342832 | 0.75 | ALDH1A1 (0.45) | HDAC6HDAC1GAAMMP1MMP3 | |
| SCHEMBL11139294 | 0.75 | MMP1 (0.41) | MMP1MMP3ALDH1A1CYP1A2 | |
| SCHEMBL7647560 | 0.75 | TRPV1 (0.47) | HDAC6HDAC3HDAC1HDAC2POLB | |
| SCHEMBL6323990 | 0.75 | TRPV1 (0.47) | HDAC6HDAC3HDAC1HDAC2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869788-B2 | DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1365023-A1 | DNA ENCODING NOVEL D-AMINOACYLASE AND PROCESS FOR PRODUCING D-AMINO ACID BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-20030207436-A1 | Dna encoding novel d-aminoacylase and process for producing d-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2003-11-06 | — | — | US | disclosed |