Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 10/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294420 | 1.00 | ACSS2 (0.60) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL29433392 | 0.92 | ACSS2 (0.70) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL21294510 | 0.92 | ACSS2 (0.70) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL21294442 | 0.92 | ACSS2 (0.70) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL29433393 | 0.92 | ACSS2 (0.70) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL21294426 | 0.91 | ACSS2 (0.60) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL29433610 | 0.86 | ACSS2 (0.83) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL21305724 | 0.86 | ACSS2 (0.83) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL21294428 | 0.83 | ACSS2 (0.84) | ACSS2HTTLMNAPKMMAPT | |
| SCHEMBL29433391 | 0.83 | ACSS2 (0.84) | ACSS2HTTLMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566092-B | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |