Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 9/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294440 | 1.00 | ACSS2 (0.62) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL29433426 | 0.97 | ACSS2 (0.63) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL28694064 | 0.97 | ACSS2 (0.63) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL29433343 | 0.93 | ACSS2 (0.65) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL21294571 | 0.93 | ACSS2 (0.65) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL21294476 | 0.89 | ACSS2 (0.67) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL21294572 | 0.86 | ACSS2 (0.67) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL21294432 | 0.85 | ACSS2 (0.66) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL21294561 | 0.85 | ACSS2 (0.71) | ACSS2ABCB1HTTLMNAPKM | |
| SCHEMBL29433300 | 0.85 | ACSS2 (0.71) | ACSS2ABCB1HTTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566092-B | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |