Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474403 | 0.80 | MAPK1 (0.43) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL8980508 | 0.79 | AKR1B1 (0.51) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL13849653 | 0.79 | KDM4E (0.50) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL17951770 | 0.77 | MAPK1 (0.68) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL13849661 | 0.77 | MAPK1 (0.46) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL1083270 | 0.69 | F11 (0.62) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL1081106 | 0.69 | CA12 (0.52) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL4288324 | 0.69 | CA12 (0.52) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL2947571 | 0.69 | CA12 (0.62) | MAPK1CA12CA9F11CA1 | |
| SCHEMBL14742903 | 0.69 | CA12 (0.65) | MAPK1CA12CA9F11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051388-A2 | QUINOLIN-2(1H)-ONE INHIBITORS OF LATE SV40 FACTOR | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-03-10 | — | — | WO | disclosed |