Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092910 | 1.00 | CA9 (0.47) | CA9KDM4EALDH1A1LMNATSHR | |
| SCHEMBL9834868 | 0.83 | AHR (0.46) | KDM4EALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL31019369 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1LMNATSHRPKM | |
| SCHEMBL23671556 | 0.72 | LMNA (0.44) | KDM4EALDH1A1LMNATSHRPKM | |
| SCHEMBL12682656 | 0.71 | CYP11B1 (0.56) | CA9ALDH1A1NPC1MAPK13MAPK12 | |
| SCHEMBL4104017 | 0.71 | CA9 (0.52) | CA9KDM4ELMNANPC1MAPK13 | |
| SCHEMBL19278654 | 0.71 | CA9 (0.52) | CA9NPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL852444 | 0.71 | CA9 (0.52) | CA9LMNANPC1MAPK13MAPK12 | |
| SCHEMBL5568453 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL9597670 | 0.71 | CA9 (0.61) | CA9ALDH1A1NPC1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051388-A2 | QUINOLIN-2(1H)-ONE INHIBITORS OF LATE SV40 FACTOR | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-03-10 | — | — | WO | disclosed |