SCHEMBL29433907

SCHEMBL29433907

O=C(O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.77
CES2 O00748 2/20 0.74
LMNA P02545 2/20 0.62
NR4A2 P43354 2/20 0.60
MRGPRX4 Q96LA9 1/20 0.60
AKR1C3 P42330 1/20 0.60
AKR1C2 P52895 1/20 0.60
MAOB P27338 1/20 0.58
KCNK3 O14649 1/20 0.58
NPSR1 Q6W5P4 1/20 0.57
P2RX1 P51575 1/20 0.57
POLB P06746 2/20 0.56
HPGD P15428 1/20 0.56
MAPT P10636 1/20 0.54
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KAT6A Q92794 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40186 1.00 SRD5A2 (0.77) SRD5A2CES2LMNANR4A2MRGPRX4
SCHEMBL28127726 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
Fluoride SCHEMBL11120479 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
SCHEMBL28119414 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
Hydrochloric Acid SCHEMBL10387616 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
SCHEMBL29208534 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
Hydrochloric Acid SCHEMBL30596522 0.98 SRD5A2 (0.74) SRD5A2CES2LMNANR4A2MRGPRX4
Ethylene SCHEMBL715875 0.96 SRD5A2 (0.72) SRD5A2CES2LMNANR4A2MRGPRX4
SCHEMBL4618676 0.94 SRD5A2 (0.70) SRD5A2CES2LMNANR4A2MRGPRX4
Dimethylamine SCHEMBL8955556 0.93 SRD5A2 (0.68) SRD5A2CES2LMNANR4A2MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122006666-A Preparation method and application of traditional Chinese medicine component magnetic nanospheres 上海工程技术大学 2026-05-12 CN claimed
CN-119486565-A Perovskite precursor solution, perovskite solar cell, preparation method and photovoltaic module 天合光能股份有限公司 2025-02-18 CN claimed
CN-117887086-A Application of halogen functionalized metal organic framework material in storage and delivery of fluorine-containing electron special gas 华为技术有限公司 2024-04-16 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-116535365-A Macrocyclic diamine derivatives and their combination with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer ITEOS比利时公司 2023-08-04 CN claimed
CN-114618441-B Controllable preparation method of MIL material and application of MIL material in separation and enrichment of polyalcohol 中国科学院大连化学物理研究所 2023-07-04 CN claimed
CN-114618441-A Controllable preparation method of MIL material and application of MIL material in separation and enrichment of polyhydric alcohol 中国科学院大连化学物理研究所 2022-06-14 CN claimed
CN-122006666-A Preparation method and application of traditional Chinese medicine component magnetic nanospheres 上海工程技术大学 2026-05-12 CN disclosed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO disclosed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO disclosed
EP-4536362-A1 TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS Incyte Corporation (US) 2025-04-16 EP disclosed
WO-2025073833-A1 OPTIMIZED PROCESS FOR THE PREPARATION OF IOPAMIDOL BRACCO IMAGING SPA (IT) 2025-04-10 WO disclosed
EP-4534526-A1 OPTIMIZED PROCESS FOR THE PREPARATION OF IOPAMIDOL Bracco Imaging SPA (IT) 2025-04-09 EP disclosed
CN-114341135-A Estrogen-related receptor alpha (ERR alpha) modulators 领先制药控股公司 2022-04-12 CN disclosed
CN-108200760-B Benzodiazepine derivatives as RSV inhibitors 英安塔制药有限公司 2022-04-01 CN disclosed
WO-2022060196-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 보로노이바이오 주식회사 2022-03-24 WO disclosed
CN-114222574-A Inhibition of USP36 瓦洛健康股份有限公司 2022-03-22 CN disclosed
CN-114206856-A Anti-malarial hexahydropyrimidine analogues UCB生物制药有限责任公司 2022-03-18 CN disclosed
CN-109563094-B (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2022-03-18 CN disclosed
CN-111018691-B Green synthesis method of aromatic acid 中国科学技术大学 2022-03-01 CN disclosed