Ethylene

Ethylene

SCHEMBL715875

C=C.O=C(O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.72
CES2 O00748 2/20 0.69
LMNA P02545 2/20 0.58
MRGPRX4 Q96LA9 1/20 0.57
NR4A2 P43354 1/20 0.57
AKR1C3 P42330 1/20 0.57
AKR1C2 P52895 1/20 0.57
MAOB P27338 1/20 0.55
KCNK3 O14649 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
P2RX1 P51575 1/20 0.54
POLB P06746 2/20 0.53
HPGD P15428 1/20 0.53
MAPT P10636 1/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
KAT6A Q92794 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40186 0.96 SRD5A2 (0.77) SRD5A2CES2LMNAMRGPRX4NR4A2
SCHEMBL29433907 0.96 SRD5A2 (0.77) SRD5A2CES2LMNAMRGPRX4NR4A2
SCHEMBL28127726 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
SCHEMBL28119414 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
Fluoride SCHEMBL11120479 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
Hydrochloric Acid SCHEMBL10387616 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
SCHEMBL29208534 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
Hydrochloric Acid SCHEMBL30596522 0.94 SRD5A2 (0.74) SRD5A2CES2LMNAMRGPRX4NR4A2
SCHEMBL4618676 0.91 SRD5A2 (0.70) SRD5A2CES2LMNAMRGPRX4NR4A2
Dimethylamine SCHEMBL8955556 0.89 SRD5A2 (0.68) SRD5A2CES2LMNAMRGPRX4NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120235148-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 US disclosed
EP-2479791-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120053287-A1 RESIN COMPOSITION FOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LTD (JP) 2012-03-01 US disclosed