Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434854 | 1.00 | MGLL (0.49) | MGLLESR1ESR2HTTHMGCR | |
| SCHEMBL23842814 | 0.86 | MGLL (0.40) | MGLLESR1ESR2HTTMAPK1 | |
| SCHEMBL29434878 | 0.79 | HTT (0.72) | HTTHMGCRRECQLMAPK1MAPT | |
| SCHEMBL875686 | 0.79 | HTT (0.72) | HTTHMGCRRECQLMAPK1MAPT | |
| SCHEMBL12016645 | 0.77 | MGLL (0.53) | MGLLESR1ESR2HTTMAPT | |
| SCHEMBL6850487 | 0.75 | MGLL (0.51) | MGLLESR1ESR2MAPK1MAPT | |
| SCHEMBL19383341 | 0.75 | MGLL (0.51) | MGLLESR1ESR2SMN1; SMN2 | |
| SCHEMBL12004629 | 0.75 | MGLL (0.51) | MGLLESR1ESR2MAPK1MAPT | |
| SCHEMBL24436801 | 0.73 | MAPK1 (0.42) | HTTHMGCRMAPK1MAPTRAB9A | |
| SCHEMBL16173473 | 0.73 | MAOB (0.46) | HTTHMGCRMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503686-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2022-03-11 | — | — | CN | disclosed |