Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266624 | 1.00 | NOS3 (0.53) | NOS3NOS1NOS2PLAUCCR1 | |
| Hydrochloric Acid SCHEMBL31037743 | 0.98 | NOS3 (0.52) | NOS3NOS1NOS2PLAUCCR1 | |
| Hydrochloric Acid SCHEMBL17893837 | 0.98 | NOS3 (0.52) | NOS3NOS1NOS2PLAUCCR1 | |
| SCHEMBL14266626 | 0.83 | CCR1 (0.53) | NOS3NOS1NOS2PLAUCCR1 | |
| SCHEMBL2624147 | 0.81 | KDM4E (0.54) | NOS3NOS1NOS2PLAUCCR1 | |
| SCHEMBL2624146 | 0.81 | NOS3 (0.53) | NOS3NOS1NOS2PLAUCCR1 | |
| SCHEMBL29435787 | 0.81 | PARP10 (0.42) | NOS3NOS1NOS2PLAUPRSS1 | |
| SCHEMBL17984689 | 0.81 | PARP10 (0.42) | NOS3NOS1NOS2PLAUPRSS1 | |
| SCHEMBL19486622 | 0.80 | PRSS1 (0.41) | PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL17984675 | 0.80 | PLAU (0.34) | NOS3NOS1NOS2PLAUPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431283-A | Preparation method of 5-bromonaphtho [1,2-b ] benzofuran | 中钢天源股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| WO-2025264837-A1 | NAPHTHYRIDINE GPR52 MODULATORS AND METHODS OF USE THEREOF | LIEBER INSTITUTE, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-119431283-A | Preparation method of 5-bromonaphtho [1,2-b ] benzofuran | 中钢天源股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-3959207-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2022-03-02 | — | — | EP | disclosed |