Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATP4A | P20648 | 3/20 | 0.37 |
| ▸ | ATP4B | P51164 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545460 | 0.89 | DDAH1 (0.41) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL373230 | 0.86 | DDAH1 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL12497852 | 0.86 | DDAH1 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL3850802 | 0.86 | AGXT (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL7563072 | 0.85 | DDAH1 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL5935831 | 0.85 | DDAH1 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL5764036 | 0.82 | CYP2C9 (0.40) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL5762134 | 0.81 | CYP2C9 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL12438867 | 0.80 | DDAH1 (0.39) | DDAH1ENGASESARM1IDO2KMT2A | |
| SCHEMBL7225187 | 0.80 | CYP2C9 (0.37) | DDAH1ENGASESARM1IDO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148314-A2 | PREPARATION OF ESOMEPRAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-12-23 | — | — | WO | disclosed |