Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409427 | 1.00 | POLB (0.64) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6753728 | 0.82 | POLB (0.62) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16586798 | 0.82 | POLB (0.67) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23525602 | 0.81 | POLB (0.58) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29440654 | 0.81 | POLB (0.58) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10972297 | 0.80 | KMT2A (0.74) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3563363 | 0.80 | POLB (0.57) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29025387 | 0.79 | POLB (0.56) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4462170 | 0.79 | ESR2 (0.72) | POLBRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30516947 | 0.78 | POLB (0.58) | POLBRAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206312-A | Topical compositions and methods for treating inflammatory skin disorders | 阿佐拉治疗股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-3955889-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2022-02-23 | — | — | EP | disclosed |