SCHEMBL29437403

SCHEMBL29437403

C[C@@H]1CN(c2ccc([N+](=O)[O-])nc2)C[C@H](C)N1

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.72
RAB9A P51151 1/20 0.71
CHRNB4 P30926 4/20 0.56
CHRNA3 P32297 4/20 0.56
CHRNB2 P17787 3/20 0.56
CHRNA4 P43681 3/20 0.56
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 2/20 0.45
KMT2A Q03164 3/20 0.43
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21541940 1.00 MAPT (0.72) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL2725735 1.00 MAPT (0.72) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL1392965 0.87 MAPT (0.89) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL2723171 0.83 MAPT (1.00) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL4825456 0.83 MAPT (1.00) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL31072982 0.83 MAPT (0.64) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL5380119 0.83 MAPT (0.64) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL29437400 0.83 MAPT (1.00) MAPTRAB9ACHRNB4CHRNA3CHRNB2
Hydrochloric Acid SCHEMBL5036857 0.82 MAPT (0.63) MAPTRAB9ACHRNB4CHRNA3CHRNB2
SCHEMBL29742107 0.81 MAPT (0.69) MAPTRAB9ACHRNB4CHRNA3CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630530-B2 FGFR inhibitor compound and use thereof HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-05-19 US disclosed
EP-4186894-B1 FGFR INHIBITOR COMPOUND AND USE THEREOF HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN) 2024-12-04 EP disclosed
US-20230192656-A1 FGFR INHIBITOR COMPOUND AND USE THEREOF HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2023-06-22 US disclosed
EP-4186894-A1 FGFR INHIBITOR COMPOUND AND USE THEREOF Henan Medinno Pharmaceutical Technology Co., Ltd. (CN) 2023-05-31 EP disclosed
CN-108283644-B Transient protection of normal cells during chemotherapy G1治疗公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630530-B2 FGFR inhibitor compound and use thereof FGFR3, FGFR1, FGFR4 MAPT 2238/4885RAB9A 1402/4885CHRNB4 4323/4885
US-20230192656-A1 FGFR INHIBITOR COMPOUND AND USE THEREOF FGFR3, FGFR1, FGFR4 MAPT 366/4885RAB9A 1673/4885CHRNB4 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.