SCHEMBL29437591

SCHEMBL29437591

CC(C)(C)[Si](C)(C)C[Si](C)(Cl)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15863920 0.77
SCHEMBL2273487 0.69
SCHEMBL31217636 0.67
SCHEMBL28773909 0.67
SCHEMBL14982846 0.65
SCHEMBL8970834 0.65
SCHEMBL31463483 0.65
SCHEMBL7120179 0.63
SCHEMBL20873161 0.61 ALDH1A1 (0.46)
SCHEMBL595 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441726-B2 Compounds and uses thereof FOGHORN THERAPEUTICS, INC. (US) 2025-10-14 US disclosed
US-12351577-B2 Inhibiting cyclic AMP-responsive element-binding protein (CREB) FORMA THERAPEUTICS, INC. (US) 2025-07-08 US disclosed
US-20250129112-A1 Novel Prodrugs Derived from Nicotinic Acid and Ribose MITOPOWER, INC. 2025-04-24 US disclosed
CN-119677738-A Compounds and uses thereof 福宏治疗公司 2025-03-21 CN disclosed
EP-4522280-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2025-03-19 EP disclosed
US-12168673-B2 Prodrugs derived from nicotinic acid and ribose MITOPOWER, INC. (US) 2024-12-17 US disclosed
EP-4463158-A2 NOVEL PRODRUGS DERIVED FROM NICOTINIC ACID AND RIBOSE Mitopower, Inc. (US) 2024-11-20 EP disclosed
US-12139487-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2024-11-12 US disclosed
CN-118922189-A Novel prodrugs derived from niacin and ribose 线粒体能量有限公司 2024-11-08 CN disclosed
CN-115297861-B Compounds and uses thereof 福宏治疗公司 2024-07-12 CN disclosed
CN-115710202-A Preparation method and application of apatazone key intermediate 江西同和药业股份有限公司 2023-02-24 CN disclosed
WO-2023021026-A1 A SYNTHETIC PATHWAY TO ESTRA-1,3,5(10)-TRIENE-3,15A,16A,17B-TETROL ASPEN OSS B.V. (NL) 2023-02-23 WO disclosed
US-20230015215-A1 EVALUATION METHOD OF DIFFERENTIATION STATE OF CELLS, AND CELL CULTURE SYSTEM HITACHI HIGH-TECH CORPORATION (JP) 2023-01-19 US disclosed
EP-4096667-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 EP disclosed
EP-4092129-A1 EVALUATION METHOD OF DIFFERENTIATION STATE OF CELLS, AND CELL CULTURE SYSTEM Hitachi High-Tech Corporation (JP) 2022-11-23 EP disclosed
CN-115297861-A Compound and use thereof 福宏治疗公司 2022-11-04 CN disclosed
US-20220213089-A1 INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) FORMA THERAPEUTICS, INC. 2022-07-07 US disclosed
US-20220169647-A1 TETRAHYDRO-IMIDAZO QUINOLINE COMPOSITIONS AS CBP/P300 INHIBITORS FORMA THERAPEUTICS, INC. 2022-06-02 US disclosed
WO-2022103899-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2022-05-19 WO disclosed
US-11292791-B2 Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors FORMA THERAPEUTICS, INC. (US) 2022-04-05 US disclosed