Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | USP8 | P40818 | 5/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074220 | 1.00 | PGR (0.38) | PGRUSP8CHEK1ABL1PDGFRB | |
| SCHEMBL21074156 | 0.95 | CHEK1 (0.38) | PGRUSP8CHEK1ABL1PDGFRB | |
| SCHEMBL29116525 | 0.86 | PGR (0.36) | PGRCHEK1ABL1PDGFRBPDGFRA | |
| SCHEMBL20496059 | 0.85 | MAPT (0.41) | PGRCHEK1KMT2AMEN1HTT | |
| SCHEMBL23839209 | 0.84 | USP8 (0.33) | PGRUSP8CHEK1ABL1PDGFRB | |
| SCHEMBL21074277 | 0.84 | USP8 (0.40) | PGRUSP8CHEK1ABL1PDGFRB | |
| SCHEMBL18758208 | 0.84 | PGR (0.44) | PGRMAPK14KMT2AMEN1HTT | |
| SCHEMBL17739615 | 0.83 | TDP1 (0.44) | MAPK14KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21074243 | 0.83 | CHEK1 (0.41) | USP8CHEK1ABL1PDGFRBPDGFRA | |
| SCHEMBL18959497 | 0.82 | PGR (0.38) | PGRKMT2AMEN1HTTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375779-B1 | 2,3-DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL AND LIGHT TRANSMITTER USING THE SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-108137554-B | Dicyanopyrazine compound, light-emitting material, light-emitting element using the light-emitting material, and method for producing 2, 5-dicyano-3, 6-dihalopyrazine | 国立大学法人九州大学 | 2022-03-18 | — | — | CN | disclosed |